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Post by dmo on Jan 22, 2021 20:51:36 GMT -6
Got my second dose of vaccine yesterday (Moderna) - been kicking my ass today. Don't want to complain about feeling like crap when I should be so grateful to (hopefully) be better protected from this damn disease. Still working for DoD so in general a pretty young and healthy population with a lot of minimally symptomatic cases but we've still had some bad outcomes and folks with significant long term sequela post Covid. This forum has been one of the few places I could come and forget about the grind of the ER from time to time. Certainly haven't had as much time to work on music as I'd like - but it's the path I chose over music in my youth. My retirement goal remains seeing if I can re-wire my brain from science back to creativity, guess I can wait a little longer. I pray that we get this vaccination roll out going and that we minimize future risk for all our families soon. Stay safe out there
Bill
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Post by svart on Jan 23, 2021 8:36:31 GMT -6
I know a handful of people who've received the second dose and all of them have had the same reaction, some needing a few days of recovery. It's a known issue and it's just the body reaction to the foreign material actually working.
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Post by dmo on Jan 23, 2021 18:44:25 GMT -6
So ended up having to call out today - something I rarely do. Having had more vaccinations that the average person (another "benefit" of former military life) this one hit me harder than I expected and is probably the most debilitating post vaccine reaction I've ever had. Take home point - try to plan your vaccines so that you can take a day or 2 to recover if needed.
Probably shouldn't have tried to post last night, temp was 102.4 when I checked so apologize for the somewhat random flight of ideas. Did appreciate Svart making sure I understood the pathophysiology though
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Post by Deleted on Jan 24, 2021 9:32:15 GMT -6
Had dose #1 of Moderna a week ago. I was a bit fatigued the next day and my blood pressure was elevated for a couple of days. Other than that, not too bad. We'll see what happens when does #2 comes around. My daughter had dose #2 of Pfizer a couple of days ago. Dose #1 kicked the stuffing out of her, so we're looking at a less-than-ideal week.
I do hope that the government's increased focus on distribution (how's that for a diplomatic way of putting it) will help get the vaccine out to the whole country. My own potential immunity doesn't mean much if everyone around me can still get sick.
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Post by Ward on Jan 24, 2021 9:54:03 GMT -6
Exercise caution with everything.
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Post by Ward on Jan 24, 2021 11:27:16 GMT -6
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Post by Deleted on Jan 24, 2021 11:45:27 GMT -6
BS. Sorry but that's the nicest thing I can say about that.
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Post by Tbone81 on Jan 24, 2021 11:53:56 GMT -6
Ward, thanks for that article. It’s certainly interesting and does bring up some valid concerns, however it’s my personal and professional opinion that those adverse effects are being somewhat overstated. Or at least not being presented in context.
My day job is in critical care medicine. These days I work mostly in the NICU. We just about always see adverse effects when we vaccinate our neonates. But by “adverse” I mean that they suffer (temporarily) from the effects of acute inflammation, caused by the vaccine. These effects can be serious. But, they’re also expected and evidence of the vaccines doing what they’re supposed to do.
So while I whole heartily believe that vaccines can pose a certain danger, I also believe that you really need to take a close, nuanced look at what’s happening in context. Which isn’t easy for most people who aren’t in the medical field...hell, it’s hard for most people IN the medical field too!
For the Moderna and Pfizer Covid vaccines I can say that adverse events are being pretty closely monitored and no one, IME, is shy about speaking up when something happens. At least on my City/State.
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Post by M57 on Jan 24, 2021 12:56:06 GMT -6
BS. Sorry but that's the nicest thing I can say about that. But with the healthimpactnews.com url, it has to be reputable, right? In fact, it looks to be the quintessential one-stop site for learning the truth about Covid, coconut health, and finding peace and healing through God.
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Post by dmo on Jan 24, 2021 13:26:55 GMT -6
CDC has a specific adverse event reporting tracker app (V-safe) that you can register for once vaccinated - it requests health updates at certain intervals and if you report any significant side effects they can contact you directly for more info. There is a lot of attention on identifying potential adverse effects as this was released under emergency use and "we" (the medical community) recognize that there is potential risk - no one wants another thalidomide type event. I certainly have not seen anyone encourage under reporting adverse reactions - if anything we tend to over report to avoid missing an early trend.
I'm a member of an online Emergency Medicine group (over 22k members - almost 50% of US EM physicians) - and we are sharing reports of any adverse effects. We know there have been several anaphylactic reactions to both the Pfizer and Moderna vaccines but I am not currently aware of any deaths directly associated with vaccination. My "go to" for this is the CDC MMWR - a weekly morbidity mortality report to keep clinicians informed on developing trends.
Ward - I appreciate your concern and recommendation to approach everything with caution. One issue many folks (including us "professionals") have when looking at medical research/data is that it's not always easy to differentiate between correlation (had vaccine and died) and causality (died from the vaccine itself). I've included a link below (from a journalists perspective) that may help when reading articles
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Post by svart on Jan 24, 2021 22:56:30 GMT -6
So ended up having to call out today - something I rarely do. Having had more vaccinations that the average person (another "benefit" of former military life) this one hit me harder than I expected and is probably the most debilitating post vaccine reaction I've ever had. Take home point - try to plan your vaccines so that you can take a day or 2 to recover if needed.
Probably shouldn't have tried to post last night, temp was 102.4 when I checked so apologize for the somewhat random flight of ideas. Did appreciate Svart making sure I understood the pathophysiology though There's some talk that a harsh reaction to the first dose might mean a previous exposure to sars-cov-2. The first dose is supposed to prime the immune system by creating a protein and training your body to see it as foreign and the second is meant to cause a reaction that mobilizes the whole immune system against it.
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Post by dmo on Jan 24, 2021 23:36:08 GMT -6
One of the issues is that Moderna uses a higher volume mRNA (100 mcg) vice 30 mcg for Pfizer - so that may explain a stronger response to the 2nd vaccine. Still fairly early in roll out - from my EM group some folks are reporting more of a reaction to 1st dose Pfizer than second, and vice versa for Moderna. We'll get a better understanding over the next few months as enough data becomes available to detect trends. At the moment they both appear to provide an appropriate initial antibody response to be considered roughly 90% effective - only time will tell if one is "better" than the other.
Svart - Our staff who had previously had Covid (and a couple that we suspected but had negative confirmatory tests) and were vaccinated seemed to have a stronger reaction to the initial shot - as you noted not really unexpected as they should already have a primed immune response.
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Post by Deleted on Jan 25, 2021 7:58:22 GMT -6
I do wonder about a couple of things. In the US we currently have two vaccines and it looks like J&J will likely come on line in another month or two. These are all emergency use authorizations. At some point (barring catastrophe), they'll become fully approved. I don't really know how we get to that point.
It looks likely that we'll need periodic updates to any of the vaccines as the coronavirus mutates and more viruses appear. This happens with influenza and those flu vaccines are updated annually without huge test phases. We just go down every year and get our shots. No one should be surprised if we do the same with coronavirus. But I wonder how we get from where we are now to there.
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Post by Ward on Jan 25, 2021 11:07:31 GMT -6
The problem here, as I see it, is health authorities are lumping in proven vaccine for stable diseases with unproven vaccines for mutating viral diseases. They aren't the same... there have already been mutations, and with regards to the influenza vaccine. It's brought out for one particular most common strain of flu but not all and becomes less effective in short order.
And the worst part of it is, those who are fully believing in the ad hoc unproven vaccines spew names like 'anti-vaxxer' at those of us exercising caution and urging others to do the same. It's quite insane.
When Covid-19 first emerged, if you were even saying this virus originated in China and that closing borders was immediately necessary, you were labeled a racist.
So you'll have to forgive me for being one of the cautious ones. because what I'm seeing as an alternative is a whole lot of politics or herd mentality brainwashing, and not enough medical science. My son is a research biologist, by the way. So I've been hearing a lot of "WTF are they doing now?" since February.
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Post by ericn on Jan 26, 2021 20:12:19 GMT -6
I do wonder about a couple of things. In the US we currently have two vaccines and it looks like J&J will likely come on line in another month or two. These are all emergency use authorizations. At some point (barring catastrophe), they'll become fully approved. I don't really know how we get to that point. It looks likely that we'll need periodic updates to any of the vaccines as the coronavirus mutates and more viruses appear. This happens with influenza and those flu vaccines are updated annually without huge test phases. We just go down every year and get our shots. No one should be surprised if we do the same with coronavirus. But I wonder how we get from where we are now to there. Answer to the first question, time, nothing can simulate it, every one of the vaccines still has multiple studies / trials for different types of patients and to see long term effectiveness. All viruses mutate, so to some extent any vaccine needs some updating to stay effective, but having multiple different vaccines makes it far less likely that will mutate in a way that makes the vaccines ineffective. 99% of vaccine reactions happen right after the shot, in most cases it’s a simple allergic reaction so an eppy pen or Benadryl is useally the solution. I of course am that 1 percent where it gets weird, flu shot has brought on pancreatitis attacks within 15min. I still got the low dose flu shot and intend to get the Covid shot as soon as I can.
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Post by ericn on Jan 26, 2021 20:34:30 GMT -6
The problem here, as I see it, is health authorities are lumping in proven vaccine for stable diseases with unproven vaccines for mutating viral diseases. They aren't the same... there have already been mutations, and with regards to the influenza vaccine. It's brought out for one particular most common strain of flu but not all and becomes less effective in short order. And the worst part of it is, those who are fully believing in the ad hoc unproven vaccines spew names like 'anti-vaxxer' at those of us exercising caution and urging others to do the same. It's quite insane. When Covid-19 first emerged, if you were even saying this virus originated in China and that closing borders was immediately necessary, you were labeled a racist. So you'll have to forgive me for being one of the cautious ones. because what I'm seeing as an alternative is a whole lot of politics or herd mentality brainwashing, and not enough medical science. My son is a research biologist, by the way. So I've been hearing a lot of "WTF are they doing now?" since February. There have been mutations, only ones who are surprised by this is the media, but the best way to make these vaccines effective would have been a quick role out, we already blew that of course but so far the vaccines are still effective. The thing with the mutations, don’t pay to much attention to the location names given to them. They just mean the mutation was discovered there, doesn’t mean it originated there. Very few samples get geno typed, to expensive and time consuming. I get being hesitant, but as that 1% who probably shouldn’t get the vaccine because there is a very real chance of ending up in the hospital afterwards let me explain the numbers game; we need approx. 80% of the population to have either survived Covid or to be vaccinated, when you consider how many weird immuno suppressed people there are out there with the doubters out there and let’s not forget the children who none of the vaccines have been approved for it’s going to be hard to get to 80%. Is there a risk ? Sure but this thing really sucks and it has taken out far to many good people and way to many of the skilled people we need to treat and diagnose those who have been infected. These vaccines are far less risky for most than this virus. Yeah I had a late lunch with a virologist and a vaccine development guy who are working on the J&J version, both live in my building.
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Post by voliviavv on Mar 26, 2021 5:54:29 GMT -6
I am very glad that the vaccine has appeared in our country and is correspondingly good. Before that, I bought various vitamins and supplements on Canadian pharmacy to improve my health. This gave a good result but the risks of infection didn`t decrease. My friend now lives in Europe and the vaccine in his country is pathetic so he orders the vaccine from USA personally for himself and his family.
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Post by bgrotto on Apr 9, 2021 22:20:23 GMT -6
My wife had some pretty gnarly body aches, but that was the extent. She was able to 'jump the line' as it were thanks to her line of work. Me, I'm up for the poke next friday and looking forward to it.
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Post by LesC on Apr 9, 2021 22:42:04 GMT -6
I got my first Pfizer shot yesterday. No ill effects, other than slight tenderness if I press on the shot site. So I don't press on it.
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Post by bgrotto on Apr 9, 2021 23:40:20 GMT -6
No ill effects, other than slight tenderness if I press on the shot site. So I don't press on it. Smart! 🤣👍🏼
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Post by ragan on Apr 10, 2021 0:44:29 GMT -6
I had my second dose of Pfizer yesterday and I've felt pretty shitty today. First dose wasn't bad, I felt a tad rummy but nothing big. Second dose definitely packs a punch (for me anyway, these reactions seem to vary a lot). Low grade fever (around 100), pretty solid body aches going, chills. My wife had similar stuff though my reaction is a bit stronger than hers was. Oh well, hard not to be happy about it. I'm very glad to have my immune system get all pissed off about spike proteins. We're both too young to have been officially eligible until this week but she volunteered at one of the clinics (where you get vaccinated if you work a day) and I got on a bunch of waste dose lists, where they call you at the end of the day if they've got doses that have already been pulled and people have cancelled or not shown up. Either goes in someone's arm or the garbage and one day I got the call and gladly brought my arm down there.
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Post by keymod on Apr 10, 2021 4:37:19 GMT -6
My wife and I both got first dose Pfizer on Wednesday. I had a pretty bad headache which aspirin took care of but nothing else. Her arm was really sore for a few days but nothing else. Can't complain, except we had to wait five weeks to get the appointment and had to drive over an hour to get there.
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Post by M57 on Apr 10, 2021 9:15:19 GMT -6
Pfizer 1st dose: Immediate sense of relief and a sore arm for 2 days.
2nd dose: Slight chills overnight, just a bit tired next day, and sore arm for 1 day - but with a great sense of relief
I'll be "fully vaccinated" (add 2 weeks) by this coming Wednesday - Moving closer to a huge sense of relief.
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Post by ericn on Apr 10, 2021 10:26:11 GMT -6
Second Moderna shot on Thursday, feel like a slight flu, starting to get back to normal.
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Post by Deleted on Apr 10, 2021 10:56:02 GMT -6
Had my second Moderna about a month ago. I think that it made me feel a little ragged, but it's hard to say. I was planning to host a memorial service just a few days after the shot, so that was causing no small worry at the same time. At any rate, no fever or anything like that. My wife had 2nd Pfizer a couple of weeks back and felt really tired for a couple of days after. But not too bad.
Moderna has announced their hopes to have a booster by the end of the year with better coverage of the British and South African variants (I know this virus has no nationality, but I can't really keep up with the numbering). We'll see where we all are next spring, but I'm guessing we'll be getting boosters on a regular basis. Covid is a very successful virus, so it's going to keep churning along.
I've got no business need ever to attend another trade show. But normally I wouldn't mind another NAMM just to see old friends. But the thought of all those thousands of people milling around in close quarters pretty much puts me off my feed. Anybody who's been to NAMM a few times has surely gotten a case of NAMMthrax. And that's just ordinary stuff. But heck, I'll settle for a few concerts here and there.
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